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Creutzfeldt-Jakob disease (CJD).

Creutzfeldt-Jakob disease (CJD).

3.0 T M.R.I. – BRAIN

Clinical Information:  Abnormal behavior and memory loss.

Findings:

  • DWI restriction noted involving left frontal, bilateral parietal, bilateral insular & left temporal cortices. Changes are bilateral asymmetrical in pattern.
  • Some of these areas appear hyperintense on FLAIR images and show signal drop on ADC.
  • Diffusion restriction also noted at left basal ganglia that appears hyperintense on FLAIR images.
  • Findings suggest possibility of Creutzfeldt-Jakob Disease (CJD).

DISCUSSION: 

  • Creutzfeldt-Jakob disease (CJD) is a rare, rapidly worsening brain disorder that causes unique changes in brain tissue and affects muscle coordination thinking, and memory.
  • The two main symptoms of CJD are:
  1. Severe mental deterioration and dementia
  2. Involuntary (unwanted) muscle jerks (myoclonus) or muscle movement.


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